Leo Babauta has a great article about decluttering your mind:
You can declutter your mind with simple actions, things we’ve discussed here before, but things that are almost guaranteed to have a positive effect. Little things that can make a big difference, especially when used in combination. Choose a few to try out, and see if they work for you.
I use several of the techniques he talks about in his article, but find myself wishing I used more of them.